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Help him relax when he comes home. When your puppy gets home, give him a warm hot water bottle and put a ticking clock near his sleeping area. This imitates the heat and heartbeat of his litter mates and will soothe him in his new environment. This may be even more important for a new dog from a busy, loud shelter who's had a rough time early on. Whatever you can do to help him get comfortable in his new home will be good for both of you.
One of the cornerstones of good health for your puppy is regular veterinary care. It is crucial that your puppy maintains a nutritional diet and exercise routine to stay healthy and balanced. Plus, your vet can advise on heartworm, and flea and tick preventative care. While a lot goes into keeping your puppy in good health, it all begins with the first visit to the vet.

It typically takes 4-6 months for a puppy to be fully house trained, but some puppies may take up to a year. Size can be a predictor. For instance, smaller breeds have smaller bladders and higher metabolisms and require more frequent trips outside. Your puppy's previous living conditions are another predictor. You may find that you need to help your puppy break old habits in order to establish more desirable ones.
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