Puppies are born with a fully functional sense of smell. They are unable to open their eyes. During their first two weeks, a puppy's senses all develop rapidly. During this stage the nose is the primary sense organ used by puppies to find their mother's teats, and to locate their littermates, if they become separated by a short distance. Puppies open their eyes about nine to eleven days following birth. At first, their retinas are poorly developed and their vision is poor. Puppies are not able to see as well as adult dogs. In addition, puppies' ears remain sealed until about thirteen to seventeen days after birth, after which they respond more actively to sounds. Between two and four weeks old, puppies usually begin to growl, bite, wag their tails, and bark.
It typically takes 4-6 months for a puppy to be fully house trained, but some puppies may take up to a year. Size can be a predictor. For instance, smaller breeds have smaller bladders and higher metabolisms and require more frequent trips outside. Your puppy's previous living conditions are another predictor. You may find that you need to help your puppy break old habits in order to establish more desirable ones.