Puppies are born with a fully functional sense of smell. They are unable to open their eyes. During their first two weeks, a puppy's senses all develop rapidly. During this stage the nose is the primary sense organ used by puppies to find their mother's teats, and to locate their littermates, if they become separated by a short distance. Puppies open their eyes about nine to eleven days following birth. At first, their retinas are poorly developed and their vision is poor. Puppies are not able to see as well as adult dogs. In addition, puppies' ears remain sealed until about thirteen to seventeen days after birth, after which they respond more actively to sounds. Between two and four weeks old, puppies usually begin to growl, bite, wag their tails, and bark.[6]
Take it outside. Finally, you’re ready to test your puppy’s skills in the Great Outdoors. There will be new challenges with this step because all the sounds, smells, and sights your puppy encounters will be intriguing and new to him. Be patient and keep the first walks short. While you’re on a walk, if your puppy looks as if he’s about to lunge toward something or is about to get distracted (you’ll notice this because you will keep your eyes on him at all times), make your cue sound and move a few steps away. Then reward him with a treat for following you.
When your dog knows the release cue and how to sit on cue, put him in a sit, turn and face him, and give him a treat. Pause, and give him another treat for staying in a sit, then release him. Gradually increase the time you wait between treats (it can help to sing the ABC’s in your head and work your way up the alphabet).  If your dog gets up before the release cue, that’s ok! It just means he isn’t ready to sit for that long so you can make it easier by going back to a shorter time.

It typically takes 4-6 months for a puppy to be fully house trained, but some puppies may take up to a year. Size can be a predictor. For instance, smaller breeds have smaller bladders and higher metabolisms and require more frequent trips outside. Your puppy's previous living conditions are another predictor. You may find that you need to help your puppy break old habits in order to establish more desirable ones.
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